As exposure to many chemicals occurs mainly via contact with the skin, knowledge of this percutaneous absorption is required by the authorities and is essential to assess the operator exposure.

With more than 15 years of expertise in dermal absorption studies, our expert team can investigate the dermal penetration of your plant protection products (including biocides and biocontrols).

With this team of technical experts, a commitment to quality and a flexible approach to projects, our main objective is to support you in achieving acceptable results for your dossier in the timelines you need.

Based on Regulations:

• OECD Guideline No. 428 for in vitro tests
• OECD Guideline No. 427 for in vivo tests
• EFSA Journal 2017 Guidance
• OECD Guidance document N° 28
• OECD Guidance Notes on Dermal Absorption N° 156
• Guidance on the Biocidal Products Regulation
• ECHA Dermal Absorption of PT21 active substances

Specific expertise includes:

• Biocidal antifouling paints
• Volatile compounds such as essential oils
• Metallic formulations such as copper using ICP-MS analysis
• Formulations screening test

We conduct full GLP studies on split-thickness rat or human skin, using either radiolabeled or non-radiolabeled compound, in occlusive or non-occlusive conditions

= Target global recovery 95%